The main component of a modern treatment regimen is, as a rule, sofosbuvir. It was first synthesized by the American biopharmaceutical company Gilead Sciences and produced under the trade name Sovaldi. According to experts, the price of Sofosbuvir in the United States of America, according to various sources, varies from 85 thousand to 150 thousand dollars for a course of treatment lasting 12 weeks, in the UK – 35 thousand pounds for the same course. This is quite an impressive amount, which, unfortunately, many can not afford. Fortunately, Gilead issued licenses for the production of generics, which, in essence, are a copy of the original drug, but they are sold at much lower prices.
The reason for the significant difference in the cost of drugs is simple, and it depends on the cost of producing these same drugs. If the American company Gilead had to conduct numerous studies, synthesize various substances, conduct many tests, carry out large paper work daily, and also pay for expensive processes for approving drugs, registering and patenting new drugs, then companies that received a license from Gilead should only buy equipment and necessary components for future preparations. Hence the significant difference in cost and, accordingly, in the final cost of the finished product.
The rest of the preparations from the originals are no different and must comply with the following main requirements:
Generic gives the same treatment effectiveness and guarantees harmlessness when using it. This is called “therapeutic equivalence.”
The active ingredient (sofosbuvir, ledipasvir, daclatasvir or velpatasvir), which is part of the composition, is 100% identical to the composition of the American drug, under whose license they are produced. This is called pharmaceutical equivalence.
Generics have the same speed and degree of absorption of the active substance by the tissues of the body. This is called “biological equivalence.”
Currently, the main suppliers are China, India and Egypt. But special attention should be paid specifically to Indian medicines, because India is one of the few countries where the manufacturing process of medicines is really controlled (and with all severity). Control is carried out by Gilead itself.
The efficacy of using Indian generics has long been proven by numerous clinical studies and three-phase trials. These studies were published at the fifty-first congress of the international level, which was devoted to liver diseases. In these data, it was mentioned that after undergoing sofosbuvir therapy, a steady response was observed in almost 95% of patients, which proves the effectiveness of these drugs.
Where to buy Sofosbuvir?
For more than five years, our company has been supplying sofosbuvir, ledipasvir, daclatasvir and other Indian medicines not only to the territory of the Russian Federation, but also to the whole world. We are trusted because we work only with reliable and trusted Indian pharmaceutical companies and suppliers that have long established themselves in the field of medicine.