Sofovir antiviral drug is a generic of the well-known Sovaldi drug and is produced under strict control and licensed by Gilead, but with all this it is much more affordable. Hetero, one of the largest companies in the Indian pharmaceutical market and one of the first to launch sofosbuvir medicines, is engaged in its production. Now the drug with sofosbuvir has become available to all economic sectors of the population due to its low price compared to the American original.
Sofovir is an antiviral drug that is used to treat chronic viral hepatitis C in adults and is known as a direct-acting antiviral. Treatment with this drug occurs in combination with other medicines. Sofovir is also prescribed for patients diagnosed with liver cancer preparing for transplant to reduce the risk of reinfection. It is worth paying attention that this drug has an effect only on hepatitis C.
The main active ingredient is sofosbuvir, which stops the reproduction of the virus in the human body. Existing virus cells die within three months.
Each individual tablet contains the active substance sofosbuvir – 400 mg.
The package contains 28 tablets. In a tablet of 400 mg of the active ingredient, it is covered with an auxiliary membrane, which makes it easy to reach the stomach without dissolving prematurely in the mouth. The tablets are oval, biconvex in shape, with beveled edges, orange. Each tablet has an engraving “H” on one side and “S14” on the other.
Store Sofovir in a dry place, away from sunlight, out of the reach of children. The drug should be kept in its original, tightly closed packaging and stored only at a temperature not lower than 15 degrees and not higher than 30 C. The date of manufacture of the drug and its shelf life are always indicated on the package. In no case should you drink the drug after its expiration date, as well as if the packaging is damaged or missing.
Hetero Ltd (India)
Indications for use
- The presence of chronic viral hepatitis C
- Patients diagnosed with liver cancer preparing for transplant
The drug is not recommended for use:
- patients with hepatitis B virus;
- pregnant and lactating women, if this is not absolutely necessary. All risks and benefits must be discussed with your doctor before taking the medicine;
- patients planning a pregnancy (not only the expectant mother, but also the father)
- patients allergic to sofosbuvir or similar substances;
- patients with pancreatitis
- patients with renal failure
- patients with depression
As a result of taking Sofovir, chills, headache, mouth sores, lower back pain, rashes, and irritation may occur. There may be problems with sleep, less often – diarrhea, nausea, lack of appetite, muscle pain, cramps, and decreased concentration of attention are possible. If any of the side effects persist or worsen, seek medical advice immediately.
Interaction with other medicines
In the treatment of chronic hepatitis C, Sofosbuvir is combined with:
The choice of medicine will depend on the past treatment, the genotype of the patient’s virus, the presence or absence of any liver damage.
Sofovir is used in conjunction with other antiviral drugs
During treatment, you should refrain from activities that require increased attention and speed of reaction.
The effect of alcohol on the effect of the drug has not been established. It is advisable to consult your doctor before taking the drug. No cases of addiction to the drug have been reported.
Before using the drug, make sure that your doctor is notified of:
Pregnancy or lactation in the patient
The presence of allergic reactions or other diseasesUsing any medication
Taking vitamins and all kinds of supplements
You should definitely contact your doctor if you suffer from cardiac arrhythmias and drink a drug such as amiodarone. When used together with sofosbuvir, the risk of bradycardia increases.
Instructions for use
Adults are prescribed one tablet every day for 12 weeks. Drinking Sofovir preferably at the same time, without passes.
Method of admission
Orally, regardless of food intake. Do not chew or crush the tablet.
One tablet of 400 mg in accordance with the instructions of the attending physician and the general condition of the patient. Do not increase or decrease the dose yourself. In no case do not interrupt the course of treatment to avoid the spread of infection. Report any side effects to your doctor immediately. During the entire administration of the drug, close monitoring of liver function is necessary.